Lead Bioinformatics Scientist - Sample to Answer

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<p>Labcorp is a global leader in diagnostic testing and drug development solutions, helping healthcare providers, researchers, and patients make informed decisions that advance care. We are dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. We are leading the transformation of the genetics industry, by making clinical-grade genetic information affordable and accessible to guide health decisions across all stages of life. Join us in our mission to improve health and improve lives.</p><p></p><p>Labcorp is seeking a<b> US based remote Lead Bioinformatics Scientist </b>to join our team!</p><p></p><p><b>Job Responsibilities:</b></p><p>The Sample‑to‑Answer Center of Excellence (CoE) within the LabCorp Information Technology department manages a wide range of diagnostic tests using advanced technologies such as next‑generation sequencing and microarrays. This position provides a unique opportunity to interact with CoE personnel and gain hands‑on experience solving real‑world problems in data science and bioinformatics. The role also contributes directly to LabCorp’s research and development efforts by addressing complex data science challenges and accelerating critical production development initiatives.</p><p>Produce innovative solutions driven by exploratory data analysis from complex and high-dimensional datasets. Apply knowledge of statistics, data modeling, data sciences and artificial intelligence to recognize patterns, identify opportunities and make valuable discoveries. Use a flexible, analytical approach to design, develop, and evaluate predictive models for single-gene non-invasive Fetal Screening (NIFS). Generate and test hypotheses and be involved from ideation through delivery.</p><p></p><p><b>Key Responsibilities</b></p><ul><li>Collaborates with R&D scientists on the development of new assays, measurement technologies, and tests for evaluating clinical conditions.</li><li>Perform sophisticated analysis of genomic, transcriptomic, or proteomic datasets using state-of-the-art bioinformatics tools and NGS pipelines.</li><li>Performs statistical and bioinformatics analyses of experimental data produced by clinical testing instruments such as DNA sequencers and other molecular instruments.</li><li>Conducts data mining over internally produced and publicly available data sets.</li><li>Provides analysis information to management to aid in decision making on the development of new laboratory developed tests.</li><li>Develop statistical classifiers and decision trees integrating spanning read support, flanking-read ratios, allele dropout indicators, and confidence intervals.</li><li>Apply a wide range of bioinformatics algorithms and develop novel computational approaches.</li><li>Investigate assay limitations at the molecular level and define boundaries of clinical reporting.</li><li>Develop and optimize complex analysis pipelines based on deep knowledge of bioinformatics algorithms.</li><li>Architect production-grade Nextflow pipelines for whole-genome sequencing, including caller selection, annotation strategy (AnnotSV, Nirvana), and QC threshold design.</li><li>Lead bioinformatics proof-of-concept for sequencer transitions, including concordance analysis, metric comparison, GIAB benchmarking, and cost-benefit recommendations.</li><li>Drive improvements in accuracy, cost of goods sold (COGS), and turnaround time across the pipeline portfolio.</li><li>Establish quality control metrics and procedures to ensure data integrity across production pipelines.</li><li>Guide result interpretation and reporting standards in collaboration with clinical and commercial stakeholders.</li><li>Set QC thresholds for new sample metrics and make production-impacting recommendations.</li></ul><p></p><p><b>Minimum Qualifications</b></p><ul><li>Ph.D. in bioinformatics, computational biology, genetics, or computer science.</li><li>3 or more years of experience in biotechnology</li><li>5 or more years of experience in programming languages in bioinformatics, such as Python, R, Perl, or Java.</li></ul><p></p><p><b>Preferred Qualifications</b></p><ul><li>5 or more years of experience with high-throughput sequencing data and bioinformatics tools like BLAST, GATK, or Bowtie.</li><li>5 or more years of experience with Linux/Unix environments and high-performance computing (HPC) or cloud platforms. </li></ul><p></p><p><b>Additional Job Standards</b></p><ul><li>Ability to effectively provide guidance to junior team members, sharing your expertise and contributing to a collaborative learning environment.</li><li>Ability to demonstrate success in technical proficiency, scientific creativity, collaboration with others and independent thought.</li><li>Ability to provide evidence of relevant research expertise in the form of presentations, software, technical publications, and knowledge of applications.</li><li>Ability to demonstrate proficiency in data analysis and statistical learning.</li><li>Ability to exercise independent judgment in developing methods, techniques and evaluation criteria for obtaining results.</li></ul><p></p><p><b>Application window open through: </b>06/09/2026</p><p></p><p><b>Pay Range: </b>$120k - $150k (USD)</p><p>All job offers will be based on a candidate’s skills and prior relevant experience, <span style="overflow-wrap: break-word; display: inline; text-decoration: inherit; hyphens: auto;">applicable degrees/certifications, as</span> well as internal equity and market data. The position is also eligible for an annual bonus under the Labcorp Bonus Plan. Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.</p><p></p><p><b>Benefits: </b>Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan. Employees who are regularly scheduled to work a 7 on/7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information, please <a href="https://careers.labcorp.com/global/en/us-rewards-and-wellness" target="_blank" rel="noopener noreferrer">click here</a>. </p><p></p><p></p><p></p><p><b>Labcorp is proud to be an Equal Opportunity Employer:</b></p><p>Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law. </p><p></p><p><b>We encourage all to apply</b></p><p>If you are an individual with a disability who needs assistance using our online tools to search and apply for jobs, or needs an accommodation, please visit our <a href="https://careers.labcorp.com/global/en/accessibility" target="_blank" rel="noopener noreferrer">accessibility site</a> or contact us at <a href="mailto:Disability_apply@LabCorp.com" target="_blank" rel="noopener noreferrer">Labcorp Accessibility.</a> For more information about how we collect and store your personal data, please see our <a href="https://www.labcorp.com/about/web-privacy-policy" target="_blank" rel="noopener noreferrer">Privacy Statement</a>.</p><p></p>

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...